01 - Preheat oven to 375°F (190°C). Grease a standard 12-cup muffin tin generously or line with paper liners.
02 - Combine the diced rhubarb, ½ cup granulated sugar, and 2 tbsp melted butter in a medium bowl and toss until the rhubarb is evenly coated. Spoon a heaping tablespoon of the mixture into the bottom of each muffin cup, pressing lightly to form an even layer.
03 - In a large mixing bowl, whisk together the flour, ½ cup granulated sugar, baking powder, baking soda, and salt until well blended.
04 - In a separate bowl, whisk the melted and cooled butter, egg, buttermilk, and vanilla extract until smooth and fully incorporated.
05 - Pour the wet ingredient mixture into the dry ingredients. Fold gently with a spatula just until combined — a few small lumps are fine. Avoid overmixing to keep the muffins tender.
06 - Divide the batter evenly among the prepared muffin cups, spooning it directly over the rhubarb layer in each cup. Smooth the tops lightly.
07 - Bake for 22–25 minutes, or until a toothpick inserted into the center of a muffin comes out clean and the tops are lightly golden.
08 - Let the muffins cool in the pan for 5 minutes. Run a butter knife around the edges of each muffin, then carefully invert the pan onto a wire rack so the rhubarb layer ends up on top. Serve slightly warm or at room temperature.