01 - Preheat oven to 400°F. Line a baking sheet with parchment paper or lightly grease with cooking spray.
02 - Combine smoked paprika, garlic powder, onion powder, dried thyme, dried oregano, cayenne pepper, salt, and black pepper in a small bowl. Mix thoroughly to distribute spices evenly.
03 - Pat salmon fillets completely dry with paper towels. Brush both sides lightly with olive oil. Press Cajun spice mixture evenly onto the top and sides of each fillet, ensuring good adhesion.
04 - Place seasoned salmon fillets on the prepared baking sheet, skin-side down if applicable. Space fillets evenly to allow proper heat circulation.
05 - Whisk together honey, fresh lemon juice, and melted unsalted butter in a separate small bowl until smooth and fully incorporated.
06 - Spoon half of the honey glaze mixture evenly over the tops of the spiced salmon fillets, reserving the remainder for later.
07 - Bake for 10 to 12 minutes, or until salmon is nearly cooked through and flakes easily when tested with a fork. The internal temperature should reach 145°F.
08 - Remove from oven and brush remaining honey glaze over each fillet. Switch oven to broil and return salmon for 1 to 2 minutes until glaze bubbles and caramelizes. Watch closely to prevent burning.
09 - Transfer to serving plates. Sprinkle with fresh chopped parsley and accompany with lemon wedges if desired. Serve immediately while hot.